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Encapsulation of ovarian allograft precludes immune rejection and promotes restoration of endocrine function in immune-competent ovariectomized mice

Premature ovarian insufficiency (POI) is a significant complication of cytotoxic treatments due to extreme ovarian sensitivity to chemotherapy and radiation. POI is particularly devastating for young girls reaching puberty, because it irreversibly affects their physical and cognitive development. Ch...

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Detalles Bibliográficos
Autores principales: Day, James Ronald, David, Anu, Barbosa, Mayara Garcia de Mattos, Brunette, Margaret Ann, Cascalho, Marilia, Shikanov, Ariella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851353/
https://www.ncbi.nlm.nih.gov/pubmed/31719632
http://dx.doi.org/10.1038/s41598-019-53075-8