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Hepcidin mediates hypoferremia and reduces the growth potential of bacteria in the immediate post-natal period in human neonates

Septicemia is a leading cause of death among neonates in low-income settings, a situation that is deteriorating due to high levels of antimicrobial resistance. Novel interventions are urgently needed. Iron stimulates the growth of most bacteria and hypoferremia induced by the acute phase response is...

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Detalles Bibliográficos
Autores principales: Prentice, Sarah, Jallow, Amadou T., Sinjanka, Edrissa, Jallow, Momodou W., Sise, Ebrima A., Kessler, Noah J., Wegmuller, Rita, Cerami, Carla, Prentice, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851364/
https://www.ncbi.nlm.nih.gov/pubmed/31719592
http://dx.doi.org/10.1038/s41598-019-52908-w