Blocking connexin43 hemichannels protects mice against tumour necrosis factor-induced inflammatory shock

Upon intravenous injection of tumour necrosis factor (TNF) in mice, a systemic inflammatory response syndrome (SIRS) is initiated, characterized by an acute cytokine storm and induction of vascular hyperpermeability. Connexin43 hemichannels have been implicated in various pathological conditions, e....

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Detalles Bibliográficos
Autores principales: Delvaeye, Tinneke, De Smet, Maarten A. J., Verwaerde, Stijn, Decrock, Elke, Czekaj, Aleksandra, Vandenbroucke, Roosmarijn E., Lemeire, Kelly, Gonçalves, Amanda, Declercq, Wim, Vandenabeele, Peter, Krysko, Dmitri V., Leybaert, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851386/
https://www.ncbi.nlm.nih.gov/pubmed/31719598
http://dx.doi.org/10.1038/s41598-019-52900-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851386/
https://www.ncbi.nlm.nih.gov/pubmed/31719598
http://dx.doi.org/10.1038/s41598-019-52900-4

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