Insulin enhancement of the antitumor activity of chemotherapeutic agents in colorectal cancer is linked with downregulating PIK3CA and GRB2

The present state of cancer chemotherapy is unsatisfactory. New anticancer drugs that marginally improve the survival of patients continue to be developed at an unsustainably high cost. The study aimed to elucidate the effects of insulin (INS), an inexpensive drug with a convincing safety profile, o...

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Detalles Bibliográficos
Autores principales: Agrawal, Siddarth, Woźniak, Marta, Łuc, Mateusz, Makuch, Sebastian, Pielka, Ewa, Agrawal, Anil Kumar, Wietrzyk, Joanna, Banach, Joanna, Gamian, Andrzej, Pizon, Monika, Ziółkowski, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851401/
https://www.ncbi.nlm.nih.gov/pubmed/31719636
http://dx.doi.org/10.1038/s41598-019-53145-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851401/
https://www.ncbi.nlm.nih.gov/pubmed/31719636
http://dx.doi.org/10.1038/s41598-019-53145-x

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