Silencing of SPARC represses heterotopic ossification via inhibition of the MAPK signaling pathway

Heterotopic ossification (HO), the pathologic formation of extraskeletal bone, can be disabling and lethal. However, the underlying molecular mechanisms were largely unknown. The present study aimed to clarify the involvement of secreted protein acidic and rich in cysteine (SPARC) and the underlying...

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Detalles Bibliográficos
Autores principales: Wang, Qianjun, Yang, Qianqian, Zhang, Ali, Kang, Zhiqiang, Wang, Yingsheng, Zhang, Zhentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Gene Expression & Regulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851515/
https://www.ncbi.nlm.nih.gov/pubmed/31548362
http://dx.doi.org/10.1042/BSR20191805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851515/
https://www.ncbi.nlm.nih.gov/pubmed/31548362
http://dx.doi.org/10.1042/BSR20191805

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