Optogenetic recruitment of spinal reflex pathways from large‐diameter primary afferents in non‐transgenic rats transduced with AAV9/Channelrhodopsin 2

KEY POINTS: We demonstrated optical activation of primary somatosensory afferents with high selectivity to fast‐conducting fibres by means of adeno‐associated virus 9 (AAV9)‐mediated gene transduction in dorsal root ganglion (DRG) neurons. AVV9 expressing green fluorescent protein showed high select...

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Detalles Bibliográficos
Autores principales: Kubota, Shinji, Sidikejiang, Wupuer, Kudo, Moeko, Inoue, Ken‐ichi, Umeda, Tatsuya, Takada, Masahiko, Seki, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851594/
https://www.ncbi.nlm.nih.gov/pubmed/31397900
http://dx.doi.org/10.1113/JP278292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851594/
https://www.ncbi.nlm.nih.gov/pubmed/31397900
http://dx.doi.org/10.1113/JP278292

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