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Optogenetic recruitment of spinal reflex pathways from large‐diameter primary afferents in non‐transgenic rats transduced with AAV9/Channelrhodopsin 2
KEY POINTS: We demonstrated optical activation of primary somatosensory afferents with high selectivity to fast‐conducting fibres by means of adeno‐associated virus 9 (AAV9)‐mediated gene transduction in dorsal root ganglion (DRG) neurons. AVV9 expressing green fluorescent protein showed high select...
Autores principales: | Kubota, Shinji, Sidikejiang, Wupuer, Kudo, Moeko, Inoue, Ken‐ichi, Umeda, Tatsuya, Takada, Masahiko, Seki, Kazuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851594/ https://www.ncbi.nlm.nih.gov/pubmed/31397900 http://dx.doi.org/10.1113/JP278292 |
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