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Synaptophysin sustains presynaptic performance by preserving vesicular synaptobrevin‐II levels

The two most abundant molecules on synaptic vesicles (SVs) are synaptophysin and synaptobrevin‐II (sybII). SybII is essential for SV fusion, whereas synaptophysin is proposed to control the trafficking of sybII after SV fusion and its retrieval during endocytosis. Despite controlling key aspects of...

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Detalles Bibliográficos
Autores principales: Kokotos, Alexandros C., Harper, Callista B., Marland, Jamie R.K., Smillie, Karen J., Cousin, Michael A., Gordon, Sarah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851701/
https://www.ncbi.nlm.nih.gov/pubmed/31216055
http://dx.doi.org/10.1111/jnc.14797