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Chronic nicotine exposure attenuates the effects of Δ(9)‐tetrahydrocannabinol on anxiety‐related behavior and social interaction in adult male and female rats

INTRODUCTION: Anxiogenic and anxiolytic effects of cannabinoids are mediated by different mechanisms, including neural signaling via cannabinoid receptors (CBRs) and nicotinic cholinergic receptors (nAChRs). This study examined the effects of prior nicotine (the psychoactive component in tobacco) ex...

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Detalles Bibliográficos
Autores principales: Manwell, Laurie A., Miladinovic, Tanya, Raaphorst, Elana, Rana, Shadna, Malecki, Sarah, Mallet, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851810/
https://www.ncbi.nlm.nih.gov/pubmed/31583843
http://dx.doi.org/10.1002/brb3.1375