Fast skeletal muscle troponin activator CK‐2066260 increases fatigue resistance by reducing the energetic cost of muscle contraction

KEY POINTS: Skeletal muscle fatigue limits performance in various physical activities, with exercise intolerance being a key symptom in a broad spectrum of diseases. We investigated whether a small molecule fast skeletal troponin activator (FSTA), CK‐2066260, can mitigate muscle fatigue by reducing...

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Detalles Bibliográficos
Autores principales: Cheng, Arthur J., Hwee, Darren T., Kim, Leo H., Durham, Nickie, Yang, Hsiao T., Hinken, Aaron C., Kennedy, Adam R., Terjung, Ronald L., Jasper, Jeffrey R., Malik, Fady I., Westerblad, Håkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Muscle
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851859/
https://www.ncbi.nlm.nih.gov/pubmed/31246276
http://dx.doi.org/10.1113/JP278235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851859/
https://www.ncbi.nlm.nih.gov/pubmed/31246276
http://dx.doi.org/10.1113/JP278235

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