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Lectin bio‐layer interferometry for assessing product quality of Fc‐ glycosylated immunoglobulin G

Glycosylation, as the most prominent posttranslational modification, is recognized as an important quality attribute of monoclonal antibodies affected by various bioprocess parameters and cellular physiology. A method of lectin‐based bio‐layer interferometry (LBLI) to relatively rank galactosylation...

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Detalles Bibliográficos
Autores principales: Wallner, Jakob, Sissolak, Bernhard, Sommeregger, Wolfgang, Lingg, Nico, Striedner, Gerald, Vorauer‐Uhl, Karola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852021/
https://www.ncbi.nlm.nih.gov/pubmed/31180180
http://dx.doi.org/10.1002/btpr.2864