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Forecasting and control of lactate bifurcation in Chinese hamster ovary cell culture processes

Biomanufacturing exhibits inherent variability that can lead to variation in performance attributes and batch failure. To help ensure process consistency and product quality the development of predictive models and integrated control strategies is a promising approach. In this study, a feedback cont...

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Detalles Bibliográficos
Autores principales: Schmitt, John, Downey, Brandon, Beller, Justin, Russell, Brian, Quach, Anthony, Lyon, David, Curran, Meredith, Mulukutla, Bhanu Chandra, Chu, Chia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852022/
https://www.ncbi.nlm.nih.gov/pubmed/31062870
http://dx.doi.org/10.1002/bit.27015