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Using Yoda-1 to mimic laminar flow in vitro: A tool to simplify drug testing

The endothelium is an attractive drug target and an important site of adverse drug reactions. Endothelial dysfunction is strongly associated with inflammation and contributes to drug-induced cardiovascular toxicity. Endothelial cells in the circulation are exposed to haemodynamic forces including sh...

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Detalles Bibliográficos
Autores principales: Davies, Jessica E., Lopresto, Dora, Apta, Bonita H.R., Lin, Zhiyuan, Ma, Wenxin, Harper, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852096/
https://www.ncbi.nlm.nih.gov/pubmed/31437459
http://dx.doi.org/10.1016/j.bcp.2019.08.013