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Using Yoda-1 to mimic laminar flow in vitro: A tool to simplify drug testing
The endothelium is an attractive drug target and an important site of adverse drug reactions. Endothelial dysfunction is strongly associated with inflammation and contributes to drug-induced cardiovascular toxicity. Endothelial cells in the circulation are exposed to haemodynamic forces including sh...
Autores principales: | Davies, Jessica E., Lopresto, Dora, Apta, Bonita H.R., Lin, Zhiyuan, Ma, Wenxin, Harper, Matthew T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852096/ https://www.ncbi.nlm.nih.gov/pubmed/31437459 http://dx.doi.org/10.1016/j.bcp.2019.08.013 |
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