Generation of cattle knockout for galactose‐α1,3‐galactose and N‐glycolylneuraminic acid antigens

Two well‐characterized carbohydrate epitopes are absent in humans but present in other mammals. These are galactose‐α1,3‐galactose (αGal) and N‐glycolylneuraminic acid (Neu5Gc) which are introduced by the activities of two enzymes including α(1,3) galactosyltransferase (encoded by the GGTA1 gene) an...

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Detalles Bibliográficos
Autores principales: Perota, Andrea, Lagutina, Irina, Duchi, Roberto, Zanfrini, Elisa, Lazzari, Giovanna, Judor, Jean Paul, Conchon, Sophie, Bach, Jean Marie, Bottio, Tomaso, Gerosa, Gino, Costa, Cristina, Galiñanes, Manuel, Roussel, Jean Christian, Padler‐Karavani, Vered, Cozzi, Emanuele, Soulillou, Jean Paul, Galli, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852128/
https://www.ncbi.nlm.nih.gov/pubmed/31115108
http://dx.doi.org/10.1111/xen.12524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852128/
https://www.ncbi.nlm.nih.gov/pubmed/31115108
http://dx.doi.org/10.1111/xen.12524

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