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Insulin Stimulates PI3K/AKT and Cell Adhesion to Promote the Survival of Individualized Human Embryonic Stem Cells

Insulin is present in most maintenance media for human embryonic stem cells (hESCs), but little is known about its essential role in the cell survival of individualized cells during passage. In this article, we show that insulin suppresses caspase cleavage and apoptosis after dissociation. Insulin a...

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Detalles Bibliográficos
Autores principales: Godoy‐Parejo, Carlos, Deng, Chunhao, Liu, Weiwei, Chen, Guokai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852186/
https://www.ncbi.nlm.nih.gov/pubmed/31021484
http://dx.doi.org/10.1002/stem.3026