Clinical trial protocol for TRANSFORM-UK: A therapeutic open-label study of tocilizumab in the treatment of pulmonary arterial hypertension

Our aim is to assess the safety and potential efficacy of a novel treatment paradigm in pulmonary arterial hypertension (PAH), immunomodulation by blocking interleukin-6 (IL6) signaling with the IL6 receptor antagonist, tocilizumab. Inflammation and autoimmunity are established as important in PAH p...

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Detalles Bibliográficos
Autores principales: Hernández-Sánchez, Jules, Harlow, Louise, Church, Colin, Gaine, Sean, Knightbridge, Emily, Bunclark, Kate, Gor, Dee, Bedding, Alun, Morrell, Nicholas, Corris, Paul, Toshner, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852369/
https://www.ncbi.nlm.nih.gov/pubmed/28956500
http://dx.doi.org/10.1177/2045893217735820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852369/
https://www.ncbi.nlm.nih.gov/pubmed/28956500
http://dx.doi.org/10.1177/2045893217735820

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