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A Bioreactor Technology for Modeling Fibrosis in Human and Rodent Precision‐Cut Liver Slices

Precision cut liver slices (PCLSs) retain the structure and cellular composition of the native liver and represent an improved system to study liver fibrosis compared to two‐dimensional mono‐ or co‐cultures. The aim of this study was to develop a bioreactor system to increase the healthy life span o...

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Detalles Bibliográficos
Autores principales: Paish, Hannah L., Reed, Lee H., Brown, Helen, Bryan, Mark C., Govaere, Olivier, Leslie, Jack, Barksby, Ben S., Garcia Macia, Marina, Watson, Abigail, Xu, Xin, Zaki, Marco Y.W., Greaves, Laura, Whitehall, Julia, French, Jeremy, White, Steven A., Manas, Derek M., Robinson, Stuart M., Spoletini, Gabriele, Griffiths, Clive, Mann, Derek A., Borthwick, Lee A., Drinnan, Michael J., Mann, Jelena, Oakley, Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852483/
https://www.ncbi.nlm.nih.gov/pubmed/30963615
http://dx.doi.org/10.1002/hep.30651