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Only α‐Gal bound to lipids, but not to proteins, is transported across enterocytes as an IgE‐reactive molecule that can induce effector cell activation

BACKGROUND: The oligosaccharide galactose‐α‐1,3‐galactose (α‐Gal), present in mammalian proteins and lipids, causes an unusual delayed allergic reaction 3 to 6 hours after ingestion of mammalian meat in individuals with IgE antibodies against α‐Gal. To better understand the delayed onset of allergic...

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Detalles Bibliográficos
Autores principales: Román‐Carrasco, Patricia, Lieder, Barbara, Somoza, Veronika, Ponce, Marta, Szépfalusi, Zsolt, Martin, Diana, Hemmer, Wolfgang, Swoboda, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852507/
https://www.ncbi.nlm.nih.gov/pubmed/31102539
http://dx.doi.org/10.1111/all.13873