Diminished secretion and function of IL‐29 is associated with impaired IFN‐α response of neonatal plasmacytoid dendritic cells

Plasmacytoid dendritic cells (pDCs) are key players in the antiviral immune response and type III IFNs such as IL‐29 appear to play a pivotal role in pDC function. Pronounced susceptibility to viral infections in neonates is partly resulting from diminished antiviral immune mechanisms. Accordingly,...

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Detalles Bibliográficos
Autores principales: Wisgrill, Lukas, Wessely, Isabelle, Netzl, Antonia, Pummer, Linda, Sadeghi, Kambis, Spittler, Andreas, Berger, Angelika, Förster‐Waldl, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Host Defense & Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852569/
https://www.ncbi.nlm.nih.gov/pubmed/31211458
http://dx.doi.org/10.1002/JLB.4A0518-189R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852569/
https://www.ncbi.nlm.nih.gov/pubmed/31211458
http://dx.doi.org/10.1002/JLB.4A0518-189R

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