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Differential expression of histamine receptors in the bladder wall tissues of patients with bladder pain syndrome/interstitial cystitis – significance in the responsiveness to antihistamine treatment and disease symptoms

BACKGROUND: Activation of mast cells plays an important role in the pathogenesis of bladder pain syndrome/interstitial cystitis (BPS/IC). Histamine, a mast cell-derived mediators, induced inflammation and hypersensitivity of the bladder. The present study investigated the expressions of histamine re...

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Detalles Bibliográficos
Autores principales: Shan, Hui, Zhang, Er-Wei, Zhang, Peng, Zhang, Xiao-Dong, Zhang, Ning, Du, Peng, Yang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852726/
https://www.ncbi.nlm.nih.gov/pubmed/31718622
http://dx.doi.org/10.1186/s12894-019-0548-3