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BRM: the core ATPase subunit of SWI/SNF chromatin-remodelling complex—a tumour suppressor or tumour-promoting factor?

BRM (BRAHMA) is a core, SWI2/SNF2-type ATPase subunit of SWI/SNF chromatin-remodelling complex (CRC) involved in various important regulatory processes including development. Mutations in SMARCA2, a BRM-encoding gene as well as overexpression or epigenetic silencing were found in various human disea...

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Detalles Bibliográficos
Autores principales: Jancewicz, Iga, Siedlecki, Janusz A., Sarnowski, Tomasz J., Sarnowska, Elzbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852734/
https://www.ncbi.nlm.nih.gov/pubmed/31722744
http://dx.doi.org/10.1186/s13072-019-0315-4