Cargando…
BRM: the core ATPase subunit of SWI/SNF chromatin-remodelling complex—a tumour suppressor or tumour-promoting factor?
BRM (BRAHMA) is a core, SWI2/SNF2-type ATPase subunit of SWI/SNF chromatin-remodelling complex (CRC) involved in various important regulatory processes including development. Mutations in SMARCA2, a BRM-encoding gene as well as overexpression or epigenetic silencing were found in various human disea...
Autores principales: | Jancewicz, Iga, Siedlecki, Janusz A., Sarnowski, Tomasz J., Sarnowska, Elzbieta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852734/ https://www.ncbi.nlm.nih.gov/pubmed/31722744 http://dx.doi.org/10.1186/s13072-019-0315-4 |
Ejemplares similares
-
SWI/SNF chromatin remodeling complex and glucose metabolism are deregulated in advanced bladder cancer
por: Stachowiak, Malgorzata, et al.
Publicado: (2020) -
Advanced adenoid cystic carcinoma (ACC) is featured by SWI/SNF chromatin remodeling complex aberrations
por: Jagielska, Beata, et al.
Publicado: (2018) -
Loss of the SWI/SNF ATPase subunits BRM and BRG1 drives lung cancer development
por: Marquez-Vilendrer, Stefanie B., et al.
Publicado: (2016) -
Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits
por: Raab, Jesse R., et al.
Publicado: (2017) -
The silencing of the SWI/SNF subunit and anticancer gene BRM in Rhabdoid tumors
por: Kahali, Bhaskar, et al.
Publicado: (2014)