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PES1 promotes BET inhibitors resistance and cells proliferation through increasing c-Myc expression in pancreatic cancer

BACKGROUND: Overexpressed PES1 promotes carcinogenesis in various types of malignant tumors. However, the biological role and clinical significance of PES1 in pancreatic cancer are still unexplored. METHODS: The expression level of PES1 in pancreatic cancer cell lines and pancreatic cancer patient s...

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Detalles Bibliográficos
Autores principales: Jin, Xin, Fang, Rui, Fan, Ping, Zeng, Lipeng, Zhang, Bin, Lu, Xiaoming, Liu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852745/
https://www.ncbi.nlm.nih.gov/pubmed/31718704
http://dx.doi.org/10.1186/s13046-019-1466-7