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DNA methylation of the PLIN1 promoter downregulates expression in chicken lines

Evidence suggests that Perilipin-1 (PLIN1) is subject to functional regulation by epigenetic modifications in women with obesity. However, whether chicken PLIN1 expression is regulated by DNA methylation is unknown. Here, Sequenom MassARRAY and real-time polymerase chain reaction (PCR) were conducte...

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Detalles Bibliográficos
Autores principales: Sun, Yuhang, Li, Rui, Zhai, Guiying, Zhang, Xinyang, Wang, Yuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Copernicus GmbH 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852845/
https://www.ncbi.nlm.nih.gov/pubmed/31807648
http://dx.doi.org/10.5194/aab-62-375-2019