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EZH2 upregulation by ERα induces proliferation and migration of papillary thyroid carcinoma

BACKGROUND: The incidence of papillary thyroid carcinoma (PTC) has been increasing worldwide in recent years. Therefore, novel potential therapeutic targets for PTC are urgently needed. Enhancer of zeste homolog 2 (EZH2), a methyltransferase belonging to PRC2, plays important roles in epigenetic sil...

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Detalles Bibliográficos
Autores principales: Xue, Liqiong, Yan, Hongzhu, Chen, Ying, Zhang, Qifa, Xie, Xin, Ding, Xiaoying, Wang, Xiaojing, Qian, Zhongqing, Xiao, Feng, Song, Zhiyi, Wu, Yijie, Peng, Yongde, Xu, Huanbai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852908/
https://www.ncbi.nlm.nih.gov/pubmed/31718595
http://dx.doi.org/10.1186/s12885-019-6306-9