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Human bone marrow mesenchymal stem cell-derived extracellular vesicles attenuate neuroinflammation evoked by focal brain injury in rats

BACKGROUND: Ischemic stroke is the major cause of long-term severe disability and death in aged population. Cell death in the infarcted region of the brain induces immune reaction leading to further progression of tissue damage. Immunomodulatory function of mesenchymal stem cells (MSCs) has been sho...

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Detalles Bibliográficos
Autores principales: Dabrowska, Sylwia, Andrzejewska, Anna, Strzemecki, Damian, Muraca, Maurizio, Janowski, Miroslaw, Lukomska, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852925/
https://www.ncbi.nlm.nih.gov/pubmed/31722731
http://dx.doi.org/10.1186/s12974-019-1602-5