Monoamine oxidase-A activity is required for clonal tumorsphere formation by human breast tumor cells

BACKGROUND: Breast tumor growth and recurrence are driven by an infrequent population of breast tumor-initiating cells (BTIC). We and others have reported that the frequency of BTIC is orders of magnitude higher when breast tumor cells are propagated in vitro as clonal spheres, termed tumorspheres,...

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Detalles Bibliográficos
Autores principales: Gwynne, William D., Shakeel, Mirza S., Wu, Jianhan, Hallett, Robin M., Girgis-Gabardo, Adele, Dvorkin-Gheva, Anna, Hassell, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852929/
https://www.ncbi.nlm.nih.gov/pubmed/31754354
http://dx.doi.org/10.1186/s11658-019-0183-8