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Monoamine oxidase-A activity is required for clonal tumorsphere formation by human breast tumor cells
BACKGROUND: Breast tumor growth and recurrence are driven by an infrequent population of breast tumor-initiating cells (BTIC). We and others have reported that the frequency of BTIC is orders of magnitude higher when breast tumor cells are propagated in vitro as clonal spheres, termed tumorspheres,...
Autores principales: | Gwynne, William D., Shakeel, Mirza S., Wu, Jianhan, Hallett, Robin M., Girgis-Gabardo, Adele, Dvorkin-Gheva, Anna, Hassell, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852929/ https://www.ncbi.nlm.nih.gov/pubmed/31754354 http://dx.doi.org/10.1186/s11658-019-0183-8 |
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