Cargando…

The impact of genetic background and cell lineage on the level and pattern of gene expression in position effect variegation

BACKGROUND: Chromatin-based transcriptional silencing is often described as a stochastic process, largely because of the mosaic expression observed in position effect variegation (PEV), where a euchromatic reporter gene is silenced in some cells as a consequence of juxtaposition with heterochromatin...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Sidney H., Elgin, Sarah C. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852933/
https://www.ncbi.nlm.nih.gov/pubmed/31722719
http://dx.doi.org/10.1186/s13072-019-0314-5