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The impact of genetic background and cell lineage on the level and pattern of gene expression in position effect variegation
BACKGROUND: Chromatin-based transcriptional silencing is often described as a stochastic process, largely because of the mosaic expression observed in position effect variegation (PEV), where a euchromatic reporter gene is silenced in some cells as a consequence of juxtaposition with heterochromatin...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852933/ https://www.ncbi.nlm.nih.gov/pubmed/31722719 http://dx.doi.org/10.1186/s13072-019-0314-5 |