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MTHFR C677T genetic polymorphism in combination with serum vitamin B(2), B(12) and aberrant DNA methylation of P16 and P53 genes in esophageal squamous cell carcinoma and esophageal precancerous lesions: a case–control study

BACKGROUND: The study aimed to explore the associations between the interactions of serum vitamin B(2) or B(12) levels, aberrant DNA methylation of p16 or p53 and MTHFR C677T polymorphism and the risks of esophageal squamous cell carcinoma (ESCC) and esophageal precancerous lesion (EPL). METHODS: 20...

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Detalles Bibliográficos
Autores principales: Pan, Da, Su, Ming, Huang, Guiling, Luo, Pengfei, Zhang, Ting, Fu, Lingmeng, Wei, Jie, Wang, Shaokang, Sun, Guiju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852963/
https://www.ncbi.nlm.nih.gov/pubmed/31754346
http://dx.doi.org/10.1186/s12935-019-1012-x