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Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma

BACKGROUND: Uveal melanoma (UM) is the most common primary intraocular tumor. Hepatic metastasis is the major and direct death-related reason in UM patients. Given that cancer stem-like cells (CSCs) are roots of metastasis, targeting CSCs may be a promising strategy to overcome hepatic metastasis in...

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Detalles Bibliográficos
Autores principales: Zhou, Jingfeng, Liu, Shenglan, Wang, Yun, Dai, Wei, Zou, Hailin, Wang, Shubo, Zhang, Jing, Pan, Jingxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852970/
https://www.ncbi.nlm.nih.gov/pubmed/31718679
http://dx.doi.org/10.1186/s12943-019-1068-1