Oxiracetam ameliorates cognitive deficits in vascular dementia rats by regulating the expression of neuronal apoptosis/autophagy-related genes associated with the activation of the Akt/mTOR signaling pathway

Oxiracetam (ORC) is a commonly used nootropic drug for improving cognition and memory impairments. The therapeutic effect and underlying mechanism of ORC in vascular dementia (VaD) treatment remain unknown. In this study, 3-month-old male Sprague-Dawley rats with permanent bilateral common carotid a...

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Detalles Bibliográficos
Autores principales: Xu, Jing, Qi, Qianqian, Lv, Peiyuan, Dong, Yanhong, Jiang, Xin, Liu, Zhijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853072/
https://www.ncbi.nlm.nih.gov/pubmed/31721903
http://dx.doi.org/10.1590/1414-431X20198371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853072/
https://www.ncbi.nlm.nih.gov/pubmed/31721903
http://dx.doi.org/10.1590/1414-431X20198371

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