Clinical Trial in a Dish: Personalized Stem Cell–Derived Cardiomyocyte Assay Compared With Clinical Trial Results for Two QT‐Prolonging Drugs

Induced pluripotent stem cells (iPSCs) have shown promise in investigating donor‐specific phenotypes and pathologies. The iPSC‐derived cardiomyocytes (iPSC‐CMs) could potentially be utilized in personalized cardiotoxicity studies, assessing individual proarrhythmic risk. However, it is unclear how c...

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Detalles Bibliográficos
Autores principales: Blinova, Ksenia, Schocken, Derek, Patel, Dakshesh, Daluwatte, Chathuri, Vicente, Jose, Wu, Joseph C., Strauss, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853144/
https://www.ncbi.nlm.nih.gov/pubmed/31328865
http://dx.doi.org/10.1111/cts.12674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853144/
https://www.ncbi.nlm.nih.gov/pubmed/31328865
http://dx.doi.org/10.1111/cts.12674

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