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A Physiologically‐Based Pharmacokinetic Model for Targeting Calcitriol‐Conjugated Quantum Dots to Inflammatory Breast Cancer Cells

Quantum dots (QDs) conjugated with 1,25 dihydroxyvitamin D3 (calcitriol) and Mucin‐1 (MUC‐1) antibodies (SM3) have been found to target inflammatory breast cancer (IBC) tumors and reduce proliferation, migration, and differentiation of these tumors in mice. A physiologically‐based pharmacokinetic mo...

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Detalles Bibliográficos
Autores principales: Forder, James, Smith, Mallory, Wagner, Margot, Schaefer, Rachel J., Gorky, Jonathon, van Golen, Kenneth L., Nohe, Anja, Dhurjati, Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853145/
https://www.ncbi.nlm.nih.gov/pubmed/31305024
http://dx.doi.org/10.1111/cts.12664