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A Physiologically‐Based Pharmacokinetic Model for Targeting Calcitriol‐Conjugated Quantum Dots to Inflammatory Breast Cancer Cells
Quantum dots (QDs) conjugated with 1,25 dihydroxyvitamin D3 (calcitriol) and Mucin‐1 (MUC‐1) antibodies (SM3) have been found to target inflammatory breast cancer (IBC) tumors and reduce proliferation, migration, and differentiation of these tumors in mice. A physiologically‐based pharmacokinetic mo...
Autores principales: | Forder, James, Smith, Mallory, Wagner, Margot, Schaefer, Rachel J., Gorky, Jonathon, van Golen, Kenneth L., Nohe, Anja, Dhurjati, Prasad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853145/ https://www.ncbi.nlm.nih.gov/pubmed/31305024 http://dx.doi.org/10.1111/cts.12664 |
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