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Clinical Pharmacology‐Driven Translational Research to Optimize Bedside Therapeutics of Sotalol Therapy

Oral sotalol, used in adults for sinus rhythm control, is initiated at 80 mg b.i.d. and titrated to a maximum safe dose. The US Food and Drug Administration recommends monitoring the corrected QT interval (QT(c)) for at least 3 days, until steady‐state exposure of the drug is reached, before patient...

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Detalles Bibliográficos
Autores principales: Dahmane, Elyes, Tang, Kathy, Gobburu, Jogarao V.S., Mattingly, T. Joseph, Reed, Brent N., See, Vincent Y., Ayres, Joshuha, Ivaturi, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853149/
https://www.ncbi.nlm.nih.gov/pubmed/31328888
http://dx.doi.org/10.1111/cts.12670