Pharmacokinetic and Pharmacodynamic Effects of Oral CXA‐10, a Nitro Fatty Acid, After Single and Multiple Ascending Doses in Healthy and Obese Subjects

10‐nitro‐9(E)‐octadec‐9‐enoic acid (CXA‐10), a novel nitro fatty acid compound, demonstrates potential as a therapeutic agent in multiple disease indications in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles. Phase I studies were conducted in hea...

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Detalles Bibliográficos
Autores principales: Garner, Rachel M., Mould, Diane R., Chieffo, Carla, Jorkasky, Diane K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853153/
https://www.ncbi.nlm.nih.gov/pubmed/31343124
http://dx.doi.org/10.1111/cts.12672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853153/
https://www.ncbi.nlm.nih.gov/pubmed/31343124
http://dx.doi.org/10.1111/cts.12672

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