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Prostate-specific Membrane Antigen Heterogeneity and DNA Repair Defects in Prostate Cancer

BACKGROUND: Prostate-specific membrane antigen (PSMA; folate hydrolase) prostate cancer (PC) expression has theranostic utility. OBJECTIVE: To elucidate PC PSMA expression and associate this with defective DNA damage repair (DDR). DESIGN, SETTING, AND PARTICIPANTS: Membranous PSMA (mPSMA) expression...

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Detalles Bibliográficos
Autores principales: Paschalis, Alec, Sheehan, Beshara, Riisnaes, Ruth, Rodrigues, Daniel Nava, Gurel, Bora, Bertan, Claudia, Ferreira, Ana, Lambros, Maryou B.K., Seed, George, Yuan, Wei, Dolling, David, Welti, Jon C., Neeb, Antje, Sumanasuriya, Semini, Rescigno, Pasquale, Bianchini, Diletta, Tunariu, Nina, Carreira, Suzanne, Sharp, Adam, Oyen, Wim, de Bono, Johann S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853166/
https://www.ncbi.nlm.nih.gov/pubmed/31345636
http://dx.doi.org/10.1016/j.eururo.2019.06.030