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Discovery and evaluation of novel synthetic 5-alkyl-4-oxo-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoxaline-1-carbox-amide derivatives as anti-inflammatory agents

To develop novel anti-inflammatory agents, a series of 5-alkyl-4-oxo-4,5-dihydro-[1, 2, 4]triazolo[4,3-a]quinoxaline-1-carboxamide derivatives were designed, synthesised, and evaluated for anti-inflammatory effects using RAW264.7 cells. Structures of the synthesised compounds were determined using (...

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Detalles Bibliográficos
Autores principales: Shen, Qing-Kun, Gong, Guo-Hua, Li, Gao-, Jin, Mei-, Cao, Li-Hua, Quan, Zhe-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853232/
https://www.ncbi.nlm.nih.gov/pubmed/31707866
http://dx.doi.org/10.1080/14756366.2019.1680658