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Fibrogenic Activity of MECP2 Is Regulated by Phosphorylation in Hepatic Stellate Cells
BACKGROUND & AIMS: Methyl-CpG binding protein 2, MECP2, which binds to methylated regions of DNA to regulate transcription, is expressed by hepatic stellate cells (HSCs) and is required for development of liver fibrosis in mice. We investigated the effects of MECP2 deletion from HSCs on their tr...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
W.B. Saunders
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853276/ https://www.ncbi.nlm.nih.gov/pubmed/31352003 http://dx.doi.org/10.1053/j.gastro.2019.07.029 |