Fibrogenic Activity of MECP2 Is Regulated by Phosphorylation in Hepatic Stellate Cells

BACKGROUND & AIMS: Methyl-CpG binding protein 2, MECP2, which binds to methylated regions of DNA to regulate transcription, is expressed by hepatic stellate cells (HSCs) and is required for development of liver fibrosis in mice. We investigated the effects of MECP2 deletion from HSCs on their tr...

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Detalles Bibliográficos
Autores principales: Moran-Salvador, Eva, Garcia-Macia, Marina, Sivaharan, Ashwin, Sabater, Laura, Zaki, Marco Y.W., Oakley, Fiona, Knox, Amber, Page, Agata, Luli, Saimir, Mann, Jelena, Mann, Derek A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853276/
https://www.ncbi.nlm.nih.gov/pubmed/31352003
http://dx.doi.org/10.1053/j.gastro.2019.07.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853276/
https://www.ncbi.nlm.nih.gov/pubmed/31352003
http://dx.doi.org/10.1053/j.gastro.2019.07.029

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