TMC1 is an essential component of a leak channel that modulates tonotopy and excitability of auditory hair cells in mice

Hearing sensation relies on the mechano-electrical transducer (MET) channel of cochlear hair cells, in which transmembrane channel-like 1 (TMC1) and transmembrane channel-like 2 (TMC2) have been proposed to be the pore-forming subunits in mammals. TMCs were also found to regulate biological processe...

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Detalles Bibliográficos
Autores principales: Liu, Shuang, Wang, Shufeng, Zou, Linzhi, Li, Jie, Song, Chenmeng, Chen, Jiaofeng, Hu, Qun, Liu, Lian, Huang, Pingbo, Xiong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853638/
https://www.ncbi.nlm.nih.gov/pubmed/31661074
http://dx.doi.org/10.7554/eLife.47441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853638/
https://www.ncbi.nlm.nih.gov/pubmed/31661074
http://dx.doi.org/10.7554/eLife.47441

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