vulcanSpot: a tool to prioritize therapeutic vulnerabilities in cancer

MOTIVATION: Genetic alterations lead to tumor progression and cell survival but also uncover cancer-specific vulnerabilities on gene dependencies that can be therapeutically exploited. RESULTS: vulcanSpot is a novel computational approach implemented to expand the therapeutic options in cancer beyon...

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Detalles Bibliográficos
Autores principales: Perales-Patón, Javier, Di Domenico, Tomás, Fustero-Torre, Coral, Piñeiro-Yáñez, Elena, Carretero-Puche, Carlos, Tejero, Héctor, Valencia, Alfonso, Gómez-López, Gonzalo, Al-Shahrour, Fátima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853644/
https://www.ncbi.nlm.nih.gov/pubmed/31173067
http://dx.doi.org/10.1093/bioinformatics/btz465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853644/
https://www.ncbi.nlm.nih.gov/pubmed/31173067
http://dx.doi.org/10.1093/bioinformatics/btz465

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