Cell-level somatic mutation detection from single-cell RNA sequencing

MOTIVATION: Both single-cell RNA sequencing (scRNA-seq) and DNA sequencing (scDNA-seq) have been applied for cell-level genomic profiling. For mutation profiling, the latter seems more natural. However, the task is highly challenging due to the limited input materials from only two copies of DNA mol...

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Detalles Bibliográficos
Autores principales: Vu, Trung Nghia, Nguyen, Ha-Nam, Calza, Stefano, Kalari, Krishna R, Wang, Liewei, Pawitan, Yudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853710/
https://www.ncbi.nlm.nih.gov/pubmed/31028395
http://dx.doi.org/10.1093/bioinformatics/btz288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853710/
https://www.ncbi.nlm.nih.gov/pubmed/31028395
http://dx.doi.org/10.1093/bioinformatics/btz288

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