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Cefiderocol: A Novel Siderophore Cephalosporin Defeating Carbapenem-resistant Pathogens
Cefiderocol, a novel siderophore cephalosporin in late-stage clinical development, utilizes a “Trojan horse” active transport mechanism to enter bacteria and has proven in vitro activity against carbapenem-resistant gram-negative pathogens, including those with major carbapenem-resistance mechanisms...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853757/ https://www.ncbi.nlm.nih.gov/pubmed/31724046 http://dx.doi.org/10.1093/cid/ciz823 |