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Thermodynamics of DNA: heat capacity changes on duplex unfolding

The heat capacity change, ΔCp, accompanying the folding/unfolding of macromolecules reflects their changing state of hydration. Thermal denaturation of the DNA duplex is characterized by an increase in ΔCp but of much lower magnitude than observed for proteins. To understand this difference, the cha...

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Detalles Bibliográficos
Autores principales: Dragan, Anatoliy, Privalov, Peter, Crane-Robinson, Colyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853854/
https://www.ncbi.nlm.nih.gov/pubmed/31690971
http://dx.doi.org/10.1007/s00249-019-01403-1