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Serum d-serine accumulation after proximal renal tubular damage involves neutral amino acid transporter Asc-1

Chiral separation has revealed enantio-specific changes in blood and urinary levels of amino acids in kidney diseases. Blood d-/l-serine ratio has been identified to have a correlation with creatinine-based kidney function. However, the mechanism of distinctive behavior in serine enantiomers is not...

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Detalles Bibliográficos
Autores principales: Suzuki, Masataka, Gonda, Yusuke, Yamada, Marina, Vandebroek, Arno A., Mita, Masashi, Hamase, Kenji, Yasui, Masato, Sasabe, Jumpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853873/
https://www.ncbi.nlm.nih.gov/pubmed/31723194
http://dx.doi.org/10.1038/s41598-019-53302-2