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Multisite phosphorylation drives phenotypic variation in (p)ppGpp synthetase-dependent antibiotic tolerance

Isogenic populations of cells exhibit phenotypic variability that has specific physiological consequences. Individual bacteria within a population can differ in antibiotic tolerance, but whether this variability can be regulated or is generally an unavoidable consequence of stochastic fluctuations i...

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Detalles Bibliográficos
Autores principales: Libby, Elizabeth A., Reuveni, Shlomi, Dworkin, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853874/
https://www.ncbi.nlm.nih.gov/pubmed/31723135
http://dx.doi.org/10.1038/s41467-019-13127-z