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Multisite phosphorylation drives phenotypic variation in (p)ppGpp synthetase-dependent antibiotic tolerance
Isogenic populations of cells exhibit phenotypic variability that has specific physiological consequences. Individual bacteria within a population can differ in antibiotic tolerance, but whether this variability can be regulated or is generally an unavoidable consequence of stochastic fluctuations i...
Autores principales: | Libby, Elizabeth A., Reuveni, Shlomi, Dworkin, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853874/ https://www.ncbi.nlm.nih.gov/pubmed/31723135 http://dx.doi.org/10.1038/s41467-019-13127-z |
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